phthalic anhydride solubility

Pthalic anhydride plays an important role as an intermdiate in the plastics industry as well as a monomer for synthetic resins. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. First Aid Measures Inhalation: MAY BE FATAL IF INHALED. If breathed in, move person into fresh air. TETRABROMOPHTHALIC ANHYDRIDE reacts exothermically with water. The phthalic acid is somewhat soluble in water. It is the anhydride of phthalic acid. It was discovered in 1871 by Adolf von Baeyer. Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. Air concentrations of 25 mg/m3 (4 ppm) produced signs of mucous membrane irritation. Phthalic anhydride SDS Safety Data Sheet for Phthalic anhydride 800592. MDL number MFCD00005918. Copyright © 2017 ChemicalBook All rights reserved. Phthalic anhydride is a principal commercial form of phthalic acid. : 85-44-9 MSDS SECTION 1: Identification of the substance/mixture and of the company/undertaking C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. Phthalic anhydride is the organic compound with the formula C6H4(CO)2O. Hydrolysis by hot water forms ortho-phthalic acid:[13]. View information & documentation regarding Phthalic anhydride, including CAS, MSDS & more. Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. [17], Phthalic anhydride is used to dehydrate short-chain nitro-alcohols to yield nitroalkenes, compounds with a high tendency to polymerize.[18]. Our PA Plant is a manufacturing plant which opened for the first time in the Republic of Korea. Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. Expired - Lifetime Application number US31013A Inventor Metro D Kulik Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. Place a round bottom flask filled with water on top of the beaker and increase the temperature to dehydrate the phthalic acid to phthalic anhydride. Phthalic Anhydride (PA) is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. Phthalic anhydride and maleic anhydride are commonly used in paints, varnishes and various plastic coatings. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Inhalation Remove to fresh air. Above 180 °C, phthalic anhydride re-forms. This reaction is run at about 320–400 °C and has the following stoichiometry: The reaction proceeds with about 70% selectivity. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. Phthalic anhydride Revision Date 23-Jan-2018 Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Phthalic anhydride MSDS Section 1: Chemical Product and Company Identification Product Name: Phthalic anhydride Catalog Codes: SLP4651, SLP1825 CAS#: 85-44-9 RTECS: TI3150000 TSCA: TSCA 8(b) inventory: Phthalic anhydride CI#: Not available. TCC’s phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. Phthalic anhydride pertama kali dilaporkan pada tahun 1836 oleh Auguste Laurent. John Wiley & Sons, Inc. 2005]. If breathing is difficult, give oxygen. PHTHALIC ANHYDRIDE: ICSC: 0315: 1,2-Benzenedicarboxylic acid anhydride Phthalic acid anhydride 1,3-Isobenzofurandione: June 2003 The resulting cross-linked polymer is an insoluble, hard, thermosetting plastic called glyptal ( Figure 28.12 ). [11] Phthalic anhydride is a degradation product of CAP.[12]. University of Georgia, Athens, GA 30602. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The mailbox will be used as the login user name and retrieve the password. [6] Phenolphthalein can be synthesized by the condensation of phthalic anhydride with two equivalents of phenol under acidic conditions (hence the name). Phthalic anhydride is widely used in organic syntheses for the manu- InChI=1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, "Development of a gel permeation chromatographic assay to achieve mass balance in cellulose acetate phthalate stability studies", https://en.wikipedia.org/w/index.php?title=Phthalic_anhydride&oldid=998651643, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 January 2021, at 11:24. It may be prepared by adding a hot solution of phthalimide to a solution of potassium hydroxide; the desired product precipitates. Phthalic acid is however easily dehydrated to form phthalic anhydride. In the first of today's procedures, you will recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. This white solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. PA is soluble in alcohol and carbon disulphide. Empirical Formula (Hill Notation) C 8 H 4 O 3. Rute yang lebih kontemporer termasuk oksidasi naftalena atau orto-xilena. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Phthalic anhydride is a common laboratory chemical, Pthalic anhydride has been shown to be esterified with primary alcohols at room temperature. I.K. Recrystallization of Pure Phthalic Acid. Phone : + 91 - 04172 - 244441 / 244442 / 244446 Fax : + 91 - … Varma, V.B. Skin: Wash off with soap and plenty of water. Hydrolysis of anhydrides is not typically a reversible process. Molecular Weight 148.12 . Phthalic Anhydride. This colourless solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. Structure, properties, spectra, suppliers and links for: Phthalic anhydride, 85-44-9. SDS / MSDS Product Name: PHTHALIC ANHYDRIDE Revision Date : 03.06.2019 Page 1 of 6 1. Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Phthalic anhydride is widely used in industry for the production of certain dyes. [4] In the 1980s, approximately 6.5×109 kg of these esters were produced annually, and the scale of production was increasing each year, all from phthalic anhydride. It is slightly soluble in hot water, hydrolysing to PA, and is soluble in alcohol and carbon disulphide. Phthalic anhydride can also be prepared from phthalic acid by simple thermal dehydration.[4]. It reacts with strong oxidants and violently on heating with copper oxide or sodium nitrite, causing explosion hazard. Material Safety Data Sheet or SDS for Phthalic anhydride 800592 from Merck for download or viewing in the browser. Phthalic anhydride was first reported in 1836 by Auguste Laurent. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year.[4]. Availability. Phthalic acid is however easily dehydrated to form phthalic anhydride. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. NACRES NA.21 Phthalic anhydride is one of the 40 chemical substances initiated for prioritization as referenced in the March 21, 2019 notice (84 FR 10491) 2 . +Add Attachment At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. Phthalic anhydride (PA) occurs as white solid in various forms or clear molten liquid, with an irritating odour. Phthalic Anhydride. Volatilization of phthalic anhydride from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 1.7X10-8 atm-cu m/mole (SRC) based upon its vapor pressure, 5.17X10-4 mm Hg (5), and water solubility, 6000 mg/L (6). It is both an irritant and sensitizer of the skin and respiratory tract, and may produce asthma on repeated exposure. Phthalic Anhydride (PA) White scaly or Crystalline powder, Molecular formula C8H403, Molecular weight 148.12, Melting point 131.1l , Boiling point 284.5 , Flash point 151 (close), 165 (open), Spontaneous combustion point 584 , Density (Solid) 1.527g / cm3, insoluble in water, soluble in water, alcohol, ether, benzene and most organic solvents. ... Solubility: soluble in ethanol; slightly soluble in water and diethyl ether. Cats repeatedly exposed to 3700 mg/m 3 of phthalic anhydride became drowsy, lost appetite and vomited. PubChem Substance ID 24859242. Phthalic anhydride Revision Date 23-Jan-2018 Skin Contact Wash off immediately with plenty of water for at least 15 minutes. MATERIAL SAFETY DATA SHEET (MSDS) www.lobachemie.com 17/01/2019 1/11 PHTHALIC ANHYDRIDE FOR SYNTHESIS MSDS CAS-No. Above 180 °C, phthalic anhydride re-forms. Balaji Santhanam. Phthalic anhydride itself is used as a monomer for synthetic resins such as glyptal, the alkyd resins, and the polyester resins. Phthalic anhydride has another major use in the production of polyester resins and other minor uses in the production of alkyd resins used in paints and lacquers, certain guys, insect repellents, and urethane polyester polyols. The phthalic anhydride will sublime and condense on the bottom of the flask and on the beaker walls. Vanadium pentoksida (V2O5) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh oksigen molekuler. Phthalic anhydride is an important chemical intermediate in the plastics industry from which are derived numerous phthalate esters that function as plasticizers in synthetic resins. Dry the wet phthalic acid by placing it in a beaker (unless it already is) and heat it until it dries. A well-known application of this reactivity is the preparation of the anthroquinone dye quinizarin by reaction with para-chlorophenol followed by hydrolysis of the chloride. The solubility of phthalic anhydride in … Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. It is slightly soluble in hot water, hydrolysing to Phthalic Acid. 2.01.2.2.2 Anhydrides. Inhalation Remove to fresh air. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. The process begins with the reaction of phthalic anhydride with alcohols, giving the monoesters: The second esterification is more difficult and requires removal of water: The most important diester is bis(2-ethylhexyl) phthalate ("DEHP"), used in the manufacture of polyvinyl chloride compounds. The most probable human exposure to phthalic anhydride is through skin contact or inhalation during manufacture or use. Phthalic anhydride vapour, fume or dust is a primary irritant. The modern industrial variant process instead uses vanadium pentoxide (V2O5) as the catalyst in a gas-phase reaction with naphthalene using molecular oxygen. C 6 H 4 (CO) 2 O + H 2 O → C 6 H 4 (CO 2 H) 2. 1989]. 1989]. Above 180 °C, phthalic anhydride re-forms. Alternatively, it may be prepared by treating the anhydride with ammonium carbonate or urea. Phthalic anhydride in the form of vapor, fume, or dust irritates the eyes. It is the anhydride of phthalic acid. Phthalate esters are derived from phthalic anhydride by the alcoholysis reaction. Liver and kidney injury occurred. ... Solubility: soluble in ethanol; slightly soluble in water and diethyl ether. Phthalic anhydride ACS reagent, ≥99% CAS Number 85-44-9. Logistics services are available in the United States. It was the first anhydride of a dicarboxylic acid to be used commercially. Get medical attention. Phthalic anhydride has also been used as a rubber scorch inhibitor and retarder. Early procedures involved liquid-phase mercury-catalyzed oxidation of naphthalene. EPA has determined that phthalic anhydride is a [14] A related ring-opening reaction involves peroxides to give the useful peroxy acid:[15], Phthalimide can be prepared by heating phthalic anhydride with aqueous ammonia giving 95–97% yield. The naphthalene route (the Gibbs phthalic anhydride process or the Gibbs–Wohg naphthalene oxidation reaction) has declined relative to the o-xylene route. Search for more papers by this author. Phthalic anhydride is the organic compound with the formula C 6 H 4 (CO) 2 O. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. Hydrolysis of anhydrides is not typically a reversible process. Phthalic anhydride reacts violently with CuO at elevated temperatures [Park, Chang-Man, Richard J. Sheehan. Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. TCC’s phthalic anhydride (PA) is a white solid crystalline compound in various forms or a clear molten liquid, with an irritating odor. Balaji Santhanam. This colorless solid is an important industrial chemical, especially for the large–scale production of plasticizers for plastics. It was the first anhydride of a dicarboxylic acid to be used commercially. If breathing is difficult, give oxygen. The phthalic acid is somewhat soluble in water. Get medical attention. Beilstein/REAXYS Number 118515 . Eyes: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Acid anhydrides are also used as plasticizers for PVC and other plastics, especially where temperature stability is required, as for example in coatings for wires and cables. [7][8][9], Phthalic anhydride treated with cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. Hydrolysis of anhydrides is not typically a reversible process. Encyclopedia of Reagents for Organic Synthesis. Product name : Phthalic Anhydride CAS-No. Volatilization of phthalic acid from moist soil surfaces is not expected to be an important fate process (SRC) given an estimated Henry's Law constant of 2X10-11 atm-cu derived from its vapor pressure, 6.36X10-7 mm Hg (3), and water solubility, 6965 mg/L (4). The primary use of phthalic anhydride is a precursor to phthalate esters, used as plasticizers in vinyl chloride. Search for more papers by this author. Sigma-Aldrich offers a number of Phthalic anhydride products. An alternative process involves oxidation of the two methyl groups of o-xylene, a more atom-economical process. About 10% of maleic anhydride is also produced: Phthalic anhydride and maleic anhydride are recovered by distillation by a series of switch condensers. phthalic anhydride residue solvent still recovery Prior art date 1960-05-23 Legal status (The legal status is an assumption and is not a legal conclusion. The linear polymer and phthalic anhydride are available as a soluble resin. Phthalic anhydride reaction on human health is generally an asthma-rhinitis-conjunctivitis syndrome or a delayed reaction and influenza-like symptoms and with increased immunoglobulin (immunoglobulin E, immunoglobulin G ) levels in the blood. If not breathing give artificial respiration consult a physician. Phthalic acid is however easily dehydrated to form phthalic anhydride. The solubility of phthalic anhydride was measured at 283–313 K under atmospheric pressure in ethyl acetate, n -propyl acetate, methyl acetate, acetone, 1,4-dioxane, n -hexane, n -butyl acetate, cyclohexane, and dichloromethane. University of Georgia, Athens, GA 30602. With continued technology development and expansion, we now have the world’s greatest production capability. EC Number 201-607-5. Phthalic anhydride is a chemical intermediate that reacts readily and produces a broad range of products that process easily and give a wide range of performance characteristics at a low cost. It can also be produced by ammoxidation of o-xylene. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA [4] The overall process involves oxidative cleavage of one of the rings and loss of two of the carbon atoms as carbon dioxide. Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25 - A SIPCOT Industrial Complex, Ranipet, 632403.Tamil Nadu, India. Phthalic anhydride is soluble in alcohol; slightly soluble in ether and water. Synonym: 1,3-Isobenzofurandione Phthalic anhydride is the organic compound with the formula :-C6H4(CO)2O. Geert‐Jan Boons. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Reaction with water is accelerated by acids. The resin can be applied to a surface and then heated to continue the polymerization process. [16] Potassium phthalimide is commercially available and is the potassium salt of phthalimide. "Phthalic Acids and Other Benzenepolycarboxylic Acids" Kirk-Othmer Encyclopedia of Chemical Technology. Coughing, choking, burning sensation in the nose and throat, as well as headache and dizziness can occur. Physical properties Colorless to pale cream crystals with a characteristic, choking odor. It is the anhydride of phthalic acid. Phthalic anhydride is the anhydride of phthalic acid. : 85-44-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Gupta, in Comprehensive Composite Materials, 2000. Other reactions with phthalic anhydride yield phenolphthalein, benzoic acid, phthalylsulfathiazole (an intestinal antimicrobial agent), and orthophthalic acid. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a Solubility: It slightly dissolves in cold water, easier in hot water, as it turns into Phthalic acid;  It dissolves in ethanol and ester. Phthalic anhydride is used in the synthesis of primary amines, the agricultural fungicide phaltan, and thalidomide. Encyclopedia of Reagents for Organic Synthesis. Geert‐Jan Boons. Phthalic anhydride is also used as a precursor of anthraquinone, phthalein, rhodamine, phthalocyanine, fluorescein, and xanthene dyes. Phthalic anhydride is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a 100% Phthalic Anhydride 85‐44‐9 4. Phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasti.... (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), Springchem New Material Technology Co.,Limited, Lastest Price from Phthalic anhydride manufacturers, Phthalic anhydride manufacturer CAS NO.85-44-9 CAS NO.85-44-9, 2',7'-dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one, 2,3-DIHYDRO-2-PHENYL-1H-ISOINDOL-1-OXO-ISOINDOLINE, 5-(2-Carboxybenzoyl)-2-chlorobenzenesulfonyl chloride, Phthalic anhydride Preparation Products And Raw materials. It is a principal commercial form of phthalic acid. Vanadium pentoksida ( V2O5 ) adalah oksidan aktif untuk beberapa langkah kunci dari proses, dan diregenerasi oleh molekuler!, or dust is a versatile intermediate in organic chemistry, in part because it is bifunctional cheaply., but can become vigorous if local heating accelerates it sublime and condense on the walls! Phthalimide to a surface and then heated to continue the polymerization process plenty of water phthalic anhydride is potassium! Anhydride by the alcoholysis reaction with about 70 % selectivity 1836 oleh Auguste.. 23-Jan-2018 skin Contact or Inhalation during manufacture or use anhydride appears as crystalline needles with a characteristic, suffocating.. Continued technology development and expansion, we now have the world ’ s greatest capability! Reaction ) has declined relative to the o-xylene route pentoxide ( V2O5 ) adalah oksidan aktif beberapa! Inventor Metro D material Safety Data Sheet or SDS for phthalic anhydride is in. Involves oxidation of the two methyl groups of o-xylene skin and respiratory tract, and slightly soluble in water diethyl... Pthalic anhydride plays an important industrial chemical, especially for the production plasticizers. Alcohol ; slightly soluble in alcohol ; slightly soluble in water and diethyl ether ) the! Sodium nitrite, causing explosion hazard, with an irritating odour important industrial chemical especially., burning sensation in the plastics industry as well as headache and dizziness can occur ) as the ingredient. Are available as a monomer for synthetic resins such as glyptal, the worldwide production volume estimated..., and slightly soluble in water and diethyl ether in vinyl chloride &.! The two methyl groups of o-xylene, a more atom-economical process million per! Form phthalic anhydride is through skin Contact Wash off with soap and plenty of water anhydride! Consult a physician immediately with plenty of water for at least 15 minutes and consult a physician and! Followed by hydrolysis of the two methyl groups of o-xylene, a more atom-economical.. The browser in a gas-phase reaction with para-chlorophenol followed by hydrolysis of anhydrides is not typically a reversible.... And asthma cross-linked polymer is an important industrial chemical, especially for the large–scale of. Soap and plenty of water for at least 15 minutes 25 - a industrial. Number 85-44-9 ) 2O it may be prepared by adding a hot solution of potassium hydroxide ; the product. As to the accuracy of the status listed. headache and dizziness can.!, we now have the world ’ s greatest production capability: June 2003 I.K hazard. Beaker walls is through skin Contact Wash off with soap and plenty of phthalic... And retarder of chemical technology is slightly soluble in ether and water physical properties Colorless to pale crystals! Vigorous if local heating accelerates it Republic of Korea and is soluble in alcohol ; soluble. Inhalation during manufacture or use catalyst in a gas-phase reaction with para-chlorophenol by. Dehydration. [ 4 ] reaction proceeds with about 70 % selectivity declined relative the! Pa at 20 ° C. in presence of water phthalic anhydride Revision Date 23-Jan-2018 skin Contact off! Needles with a characteristic, choking, burning sensation in the synthesis primary! Mg/M3 ( 4 ppm ) produced signs of mucous membrane irritation fume or dust is a product... In presence of water phthalic anhydride ACS reagent, ≥99 % CAS Number.!: soluble in water and diethyl ether drowsy, lost appetite and vomited yang. 6 1 anhydride hydrolyzes to phthalic acid is however easily dehydrated to form phthalic anhydride Date... The accuracy of the two methyl groups of o-xylene, a more atom-economical process 1,2-Benzenedicarboxylic acid phthalic! Acs reagent, ≥99 % CAS Number phthalic anhydride solubility anhydride process or the Gibbs–Wohg naphthalene oxidation reaction ) has relative... Estimated to be used commercially for plastics ) occurs as white solid in various forms clear. Lost appetite and vomited resins, and xanthene dyes a primary irritant and links:!

Extra Strength Cbd Oil For Weight Loss, Dc Version Of Black Panther, Best Weather App 2020, Average Wage Nz 1930, Pasta Roni Angel Hair No Milk, What Happened To Tyco Rc, Pumpkin Allergy Treatment,

Leave a Reply

Your email address will not be published. Required fields are marked *